Humanized mice, generated by transplanting pre-validated CD34+ human hematopoietic stem cells into immune deficient mice are extremely useful in basic and applied human disease research. HuMurine Technologies is a CRO (contract research organization) that provides specialized research services based on the Human Immune System Mouse. Both the Hu-M™ and the Hu-3GM™ mouse are stably engrafted with a functional human immune system and are ideal for doing efficacy and safety assessment of therapeutics that requires a human immune response. The Hu-M™ Mice are generated by a proprietary two-step validation process using pre-validated CD34+ human stem cells and 8 color flow cytometry. HuMurine currently offers contract research services on cancer biology (immuno-oncology), infectious diseases (vaccines, antiviral therapies and gene therapy), inflammation (cytokine release syndrome, immunity assessment), assessment of immune response against human restricted diseases (human antibody or T cell response), and gene therapies. HuMurine has expertise and proprietary protocols for the purification of human CD34+ stem cells and for the generation of humanized mice with robust and reproducible kinetics. A joint-venture with Yingeng Biologics is proposed to synergize expertise in human stem cells and humanized immune system mice and provide contract services.,Humanized mice, generated by transplanting pre-validated CD34+ human hematopoietic stem cells into immune deficient mice are extremely useful in basic and applied human disease research. HuMurine Technologies is a CRO (contract research organization) that provides specialized research services based on the Human Immune System Mouse. Both the Hu-M™ and the Hu-3GM™ mouse are stably engrafted with a functional human immune system and are ideal for doing efficacy and safety assessment of therapeutics that requires a human immune response. The Hu-M™ Mice are generated by a proprietary two-step validation process using pre-validated CD34+ human stem cells and 8 color flow cytometry. HuMurine currently offers contract research services on cancer biology (immuno-oncology), infectious diseases (vaccines, antiviral therapies and gene therapy), inflammation (cytokine release syndrome, immunity assessment), assessment of immune response against human restricted diseases (human antibody or T cell response), and gene therapies. HuMurine has expertise and proprietary protocols for the purification of human CD34+ stem cells and for the generation of humanized mice with robust and reproducible kinetics. A joint-venture with Yingeng Biologics is proposed to synergize expertise in human stem cells and humanized immune system mice and provide contract services.